BBC-British scientists discover 'universal way' to fight cancer
According to the UK Public broadcaster, British scientists have found a "universal method" for treating cancer.
According to the BBC, the discovery by a team of scientists from the University of Cardiff may allow doctors to "tune" the human immune system against cancer cells. This could open the way to a universal cure for cancer. The method has not yet been clinically tested, but researchers say it has huge potential. A summary of the work was published in the journal "Nature Immunology".
The essence of the study was to find "unusual" ways in which the immune system fights cancer. Scientists have discovered a special type of T-lymphocyte-a cell that is responsible for the immune response in the human body. However, the cell found by scientists, unlike others, can counteract different types of threats.
"There is a chance that this can cure all patients. No one thought this was possible before, "researcher Henry Siwell said in a conversation with the BBC.
On the surface of T-lymphocytes (or T-cells), there are chemical receptors that they use to identify antigens that are dangerous to the body.
The team of scientists managed to find a way to make the type of T-lymphocytes they found attack a wide range of cancer cells.
The method would be tested on lung, blood, bowel, breast, bone, prostate, ovarian, and cervical cancer cells.
The lymphocyte destroyed cancer cells and did not touch healthy ones.
How exactly the T-lymphocyte distinguishes cancer cells from healthy ones is not yet clear. Its receptor interacts with a molecule called MR1, which is on the surface of every cell in the human body.
It is believed that cancer cells "use" MR1 to disguise themselves from the immune system. However, the T-lymphocyte found in Cardiff, researchers believe, can receive a signal from MR1 that the cell's metabolism is disrupted, and that it is a tumor cell.
"We are the first to describe a T cell that detects MR1 in cancer cells. No one has done this before, " says researcher Harry Dalton.
This study is not the first in its field. Experiments on setting up the immune system against cancer have been conducted for a long time.
The most famous of these is CAR-T. this anti-leukemia drug reprograms the immune system to counteract this type of cancer. In the case of CAR-T, T-lymphocytes are genetically reprogrammed to find and destroy cancer cells.
The modified lymphocytes are then returned to the patient's body, where their number increases each time they encounter cancer cells.
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BBC-British scientists discover 'universal way' to fight cancer
According to the UK Public broadcaster, British scientists have found a "universal method" for treating cancer.
According to the BBC, the discovery by a team of scientists from the University of Cardiff may allow doctors to "tune" the human immune system against cancer cells. This could open the way to a universal cure for cancer. The method has not yet been clinically tested, but researchers say it has huge potential. A summary of the work was published in the journal "Nature Immunology".
The essence of the study was to find "unusual" ways in which the immune system fights cancer. Scientists have discovered a special type of T-lymphocyte-a cell that is responsible for the immune response in the human body. However, the cell found by scientists, unlike others, can counteract different types of threats.
"There is a chance that this can cure all patients. No one thought this was possible before, "researcher Henry Siwell said in a conversation with the BBC.
On the surface of T-lymphocytes (or T-cells), there are chemical receptors that they use to identify antigens that are dangerous to the body.
The team of scientists managed to find a way to make the type of T-lymphocytes they found attack a wide range of cancer cells.
The method would be tested on lung, blood, bowel, breast, bone, prostate, ovarian, and cervical cancer cells.
The lymphocyte destroyed cancer cells and did not touch healthy ones.
How exactly the T-lymphocyte distinguishes cancer cells from healthy ones is not yet clear. Its receptor interacts with a molecule called MR1, which is on the surface of every cell in the human body.
It is believed that cancer cells "use" MR1 to disguise themselves from the immune system. However, the T-lymphocyte found in Cardiff, researchers believe, can receive a signal from MR1 that the cell's metabolism is disrupted, and that it is a tumor cell.
"We are the first to describe a T cell that detects MR1 in cancer cells. No one has done this before, " says researcher Harry Dalton.
This study is not the first in its field. Experiments on setting up the immune system against cancer have been conducted for a long time.
The most famous of these is CAR-T. this anti-leukemia drug reprograms the immune system to counteract this type of cancer. In the case of CAR-T, T-lymphocytes are genetically reprogrammed to find and destroy cancer cells.
The modified lymphocytes are then returned to the patient's body, where their number increases each time they encounter cancer cells.
1tv.ge
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